Overnight pill Vicodin is a prescription combination medicine that contains Hydrocodone and acetaminophen. It is an opiate drug that works as a pain reliever, useful in managing multiple levels of pain with similar efficacy to morphine. Hydrocodone is an opioid substance that primarily works for pain management while acetaminophen is a non-opioid drug that works to increase the effects of Hydrocodone. Now you can easily buy vicodin online from the most trusted vendor in the USA.