Buy Norco online (hydrocodone/acetaminophen) is a combination of two medications that work together to treat pain. It attaches to certain mu-opioid receptors in your brain to lower how much pain you feel. Acetaminophen is an analgesic. Hydrocodone is an opioid analgesic that affects the brain's perception of pain, while acetaminophen is a non-opioid pain reliever that works to reduce fever and inflammation.