If you wait until the pain has become high, Hydrocodone medication may not work as well. If you have ongoing pain (such as due to cancer), your doctor may direct you to also take long-acting opioid medications. In that case, buying Hydrocodone online medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as acetaminophen, and ibuprofen) may also be prescribed with this medication. Ask your doctor or pharmacist about using HYDROCODONE with other drugs.