For treatment-resistant depression (TRD), several medications may be effective. Atypical antipsychotics like aripiprazole or quetiapine can enhance antidepressant effects. Mood stabilizers such as lithium may also help. Monoamine oxidase inhibitors (MAOIs) are an option but require dietary restrictions. Recently, ketamine and its derivative, esketamine, have shown rapid effects. Transcranial magnetic stimulation (TMS) is another non-medication approach that can be beneficial. It's crucial to consult a healthcare provider for personalized treatment options. For more information, visit https://www.delhimindclinic.com/.