How effective are antidepressants in the long-term when used without psychotherapy? Antidepressants can be effective in managing symptoms of depression and anxiety by balancing brain chemicals, but their long-term success without psychotherapy varies. While they may provide relief from mood disturbances, relying solely on medication without addressing underlying emotional or behavioral patterns can limit overall improvement. Cognitive Behavioral Therapy (CBT) and other psychotherapies help individuals develop coping strategies, identify triggers, and build emotional resilience, leading to better long-term outcomes. Without therapy, there is a higher risk of relapse once medication is discontinued. A combined approach of medication and therapy is generally recommended for sustained recovery. For professional mental health support, platforms like Best Psychiatrist in Delhi (https://www.bestpsychiatristsindelhi.com/) and Delhi Mind Clinic (https://www.delhimindclinic.com/) connect individuals with expert psychiatrists specializing in comprehensive depression treatment.