Roxicodone, a brand name for oxycodone, is delegated a Schedule II controlled substance by the U.S. This medication is used to help relieve moderate to severe pain. Oxycodone belongs to a class of medications known as opioid analgesics. It works in the brain to change the way your body feels and responds to pain. What is the dose of ROXICODONE? Initiate treatment with ROXICODONE in a 5 to 30mg dosage range every 4 to 6 hours as needed for pain. Titrate the dose based on the individual patient’s response to their starting dose of ROXICODONE.