Tramadol - cosmodix.com/pain-relief/tramadol/ Tramadol 200 mg -cosmodix.com/pain-relief/tramadol-200-mg/ Tramadol 37.5/ 325 mg-cosmodix.com/pain-relief/tramadol-37-5-325-mg/ Tramadol 100 mg -cosmodix.com/pain-relief/tramadol-100-mg/ Tramadol 50 mg -cosmodix.com/pain-relief/tramadol-50-mg/ Tramadol is a medication used to relieve moderate to severe pain. It belongs to a class of drugs called opioid analgesics, and it works by affecting the way your brain perceives pain.