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Meridia worked by inhibiting the reuptake of serotonin, norepinephrine, and to a lesser extent, dopamine. By increasing the levels of these neurotransmitters in the brain, it was thought to promote feelings of fullness and reduce food intake.
Safety Concerns: The decision to withdraw Meridia from the market was based on several safety concerns, primarily related to cardiovascular events. Studies indicated an increased risk of heart attacks, strokes, and other cardiovascular problems, especially in patients with a history of heart disease or stroke.
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