The combination of hydrocodone and acetaminophen is used to treat moderate to severe pain. Hydrocodone is a narcotic pain reliever, while acetaminophen is a non-narcotic pain reliever. Together, these medications can effectively relieve pain. The common dosage of hydrocodone/acetaminophen is 10 mg of hydrocodone and 325 mg of acetaminophen. However, it is always important to follow the instructions and dosage recommended by your doctor. Remember that this medication requires a prescription and should only be used under medical supervision. If you have any questions, I recommend that you talk to your doctor or pharmacist.