You will need a doctor’s prescription to Buy Oxycodone Online or at your local pharmacy. because it is a prohibited substance in the United States, this medication can only be obtained with a prescription. It is a prohibited substance because there is a chance that reliance on it. The purpose of this combo drug is to treat moderate to severe pain. Both an opioid painkiller ( Oxycodone) and a non-opioid painkiller are present (acetaminophen). The brain-based effects of hydrocodone alter how your body perceives and reacts to pain. Additionally, acetaminophen helps lower a fever.