Percocet is used to treat moderate to severe pain. It contains two types of pain relievers: opioids (oxycodone) and non-opioids (acetaminophen). Oxycodone works in the brain to alter how your body perceives and reacts to pain. Acetaminophen can also lower fevers. This combo medicine relieves moderate to severe pain. Please keep in mind that Percocet is not intended to treat minor discomforts like headaches or menstrual cramps. It is generally suggested for use when non-opioid treatment is ineffective, and it should not be self-prescribed.