Order link: https://cosmodix.com/pain-relief/hydrocodone/ Norco is a prescription pain medication that is used to treat moderate to severe pain. It is a combination of hydrocodone and acetaminophen. Hydrocodone is an opioid that works by binding to opioid receptors in the brain and spinal cord. This binding inhibits the transmission of pain signals to the brain, resulting in pain relief. Acetaminophen is a non-opioid pain reliever that works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation.