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The active substance avanafil is a powerful, highly selective, reversible inhibitor of PDE5 (phosphodiesterase type 5), an enzyme that naturally occurs in a man’s body during arousal and constricts blood vessels after ejaculation. Once in the blood, the drug blocks the production of PDE5, promoting relaxation of smooth muscles and blood flow to the tissues of the penis. As a result, the vessels of the penis dilate, blood circulation increases, and a high-quality and long-lasting erection occurs.
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