Today all over the world, several types of physical pain are experienced by people. The use of painkillers is increasing day by day in modern society. Pain-relief medications are used to manage short-term and long-term physical pain. Here, short-term pain is acute, and long-term pain is chronic pain. There are a variety of pharmaceutical drugs that are used to treat moderate or severe pain, which can be caused by any condition such as pre or post-surgery pain or pain after an accident etc. The two common medicines used to treat this type of pain are Ultracet and Vicodin. In this article, we will be comparing Ultracet vs Vicodin drugs their similarities, and their side effects