Granuloma annulare (GA) is a chronic skin condition characterized by raised, reddish or skin-colored bumps arranged in a ring pattern, often on the hands, feet, elbows, or knees. Although the exact cause is unknown, it is thought to be related to the immune system. For many people, granuloma annulare can be asymptomatic and self-limiting, but for others, it can be persistent and require treatment.