An opioid drug called oxycodone is used to treat moderate to severe pain. It comes in both immediate-release and extended-release oral dosage forms. For immediate-release formulations of oxycodone, the effects usually start to wear off in about 15 minutes and last for around 6 hours. Additionally available for purchase online is oxycodone combined with acetaminophen or aspirin. According to studies, 5 mg of oxycodone has around 1.5 times the effectiveness of 5 mg of morphine, making it more strong than the latter drug. In the year 1916, Germans created oxycodone from thebaine.