Hydrocodone 10-325mg is a prescription medication that combines 10 mg of hydrocodone bitartrate, an opioid analgesic, with 325 mg of acetaminophen, a non-opioid pain reliever. This combination is used to relieve moderate to severe pain. Hydrocodone works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain and the emotional response to it.