Hydrocodone 10-660mg is a medication used to treat moderate to severe pain. It is an opioid medication that works by binding to receptors in the brain and spinal cord to decrease the perception of pain. It is important to take Hydrocodone 10-660mg exactly as your doctor prescribes. Typically, it is taken every 4 to 6 hours as needed for pain relief. It can be taken with or without food, but it is recommended to take it with food to help prevent stomach upset. Hydrocodone should only be taken orally in tablet form, such as 5-325mg, 10-325mg, 10-500mg, 10-650mg, or 10-660mg doses.