Visit Now: https://bigpharmausa.com/bupropion-vs-adderall/ Although both Adderall and bupropion affect the brain, their main functions and modes of action differ. Often given for depression and seasonal affective disorder, bupropion is an antidepressant and smoking cessation aid that increases dopamine and norepinephrine levels. Despite occasionally being used off-label for ADHD, its effects are less severe than those of stimulants.