https://nuheals.com/pain-relief/norco-7-5-325-mg/ Norco 7.5/325 mg is a prescription medication that combines 7.5 mg of hydrocodone (an opioid pain reliever) and 325 mg of acetaminophen (a non-opioid pain reliever). It is used to manage moderate to severe pain that isn't adequately controlled by over-the-counter pain medications alone. While hydrocodone is the opioid component, acetaminophen works as a mild pain reliever that also helps reduce inflammation