Order Opana Online | Buy Opana Online | Overnight Fedex | Credit Card | Read the Medication Guide provided by your pharmacist before you start taking methadone and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible This prescription is utilized to encourage assuage mellow to direct torment. Methadone has a place with a class of medications known as opioid opiate analgesics. It works in the cerebrum to change how your body feels and reacts to torment