What is the role of Ambien tartare in sleeping disorders? Order Zolpidem tartare or Ambien CR is a higher dose of zolpidem medicines. And the CR stands for extended-release, and it is a two layers tablet. So the first layer releases its drug content immediately, and the second layer takes time to release additional drug content. So it has had its effect for a long time. How to take Ambien? You should take Ambien empty stomach just before your bedtime. And for the initial dose, you should use Ambien 5mg. And it would be best if you did not take higher doses of this medication without your doctor's prescription.