Piperidine alkaloids are widespread among the Apiaceae, Solanaceae, Chenopodiaceae, Fabaceae, Crassulaceae, Lycopodiaceae, and Asteraceae. They are organic compounds containing saturated heterocyclic amine ring, i.e piperidine nucleus – a six membered ring consists of five methylene bridge (-CH2-) and one amine (-NH2-) bridge. Most of the alkaloids containing the piperidine rings, including pelletierine (Punica granatum), piperine (Piper nigrum et longum), and lobeline (Lobelia inflata) are derived from lysine. Piperidine alkaloids are of interest to many researchers because of their important biological activities.