Node.js, with its event-driven, non-blocking architecture, has transformed web performance by enabling faster, scalable applications. Its single-threaded model efficiently handles multiple concurrent connections, making it ideal for real-time applications like chat apps and online gaming. The built-in V8 engine further boosts performance, while tools like clusters and load balancers ensure scalability. This guide explores strategies for leveraging Node.js web development to optimize performance, including best practices for memory management, asynchronous programming, and effective use of caching techniques.