The demand for biological and chemical samples has led to the development of nano flow liquid chromatography, which is more sensitive than conventional liquid chromatography. Chromatographic separations using flow rates in the low nanoliter per minute greatly improve concentration efficiency and analytical sensitivity.

Clinical chemistry analyzers, also referred to as biochemistry analyzers, are medical laboratory devices used to determine the concentration of certain metabolites, electrolytes, proteins, and/or drugs in samples of serum, plasma, urine, cerebrospinal fluid, and/or other body fluids. Chemical analyzers are divided into benchtops, bedside models, and high-throughput floor-based models, the most common of which is benchtops. In addition to style, instrument's throughput capacity, test speed, analysis mode, software, scalability, and reagent compatibility are key considerations when choosing a clinical analyzer to ensure that an instrument is well suited for your laboratory.

Uni Series IEX Resins UniCM, UniSP, UniQ, UniDEAE, and UniMSP are designed for the IEX purification of small proteins, peptides, oligo nucleotides, and small molecule such as antibiotics. Their supports are highly crosslinked polymethacrylate beads of uniformed particle size. Uni IEX resins have good hydrophilicity and low non-specific adsorbability by surface modification. Their smaller pore size makes them more suitable for IEX purification of small biomolecules. All of these resins meet the reproducibility, extensibility, and reliability requirements of today's industrial biological processes.

Reporter vectors containing reporter genes are usually used to assess the transfection efficiency of a target gene into a cell, as well as the protein expression of the target gene. When the promoter regions are cloned upstream of the reporter gene and enhancer elements are cloned upstream or downstream of the gene, the reporter vector allows functional identification and characterization of promoters and enhancer elements that regulate cell, tissue, and developmental definitions, since the expression of the reporter is correlated with the transcriptional activity of the reporter gene. Reporter genes can also be engineered into viral vectors to track the type of cells the virus infects, the timing and duration of expression for viral genes, and viral latency. In addition, reporter vectors can be used to monitor other processes such as recombination events, gene targeting, RNA processing, protein secretion pathways, and signal transduction pathways in cells. In a transfection experiment

Electrophoresis is a laboratory technique used to separate mixtures of DNA, RNA, or protein molecules based on their size, mass, and electrical charge. Under the influence of an electric field, charged molecules migrate to separate in a matrix, such as agarose gel, polyacrylamide gel, or capillary tube. Electrophoresis systems usually consist of modules: gel box or capillary array, power supply and buffer receptacle.

Gas chromatography packed columns are widely used in gas chromatography. The key part of a packed column is the stationary phase, which determines the application and characteristics of the column. Amerigo Scientific supplies high-quality packing materials of different sizes, polarities and materials for gas-liquid chromatography and gas-solid chromatography, including uncoated stationary phases, liquid stationary phases, supports and pre-coated liquid stationary phase packing to meet the needs of different customers. The uncoated packing materials are mainly suitable for gas-solid chromatography columns. Those materials mainly include inorganic adsorbents and porous polymer beads. We offer a wide range of adsorbents including silica gel with strong polarity, activated alumina with medium polarity, activated carbon with non-polarity and molecular sieve 13X with extremely uniform pore. Most of them can be used at high temperatures, with high adsorption capacity and good thermal stabi

Immunotoxic response can originate from direct toxicity of the pharmaceutical to components of the immune system. Direct immunotoxicity may result in either immunosuppression or immunostimulation. Alternatively, the immune system may react to chemicals in an antigen-specific way. Therefore, immunotoxicology is an important aspect of the safety evaluation of drugs and chemicals. Despite the remarkable success of rodent-based models in determining immunotoxicity, there are limitations in extrapolating the risk posed to humans. Immunotoxicological data resources derived from studies using human primary leukocytes can facilitate rational decision making for drug development.

With the enhancement of environmental awareness, it has become a general trend to replace liquid acid base catalyst with solid acid base catalyst. Compared with liquid catalyst, solid catalyst has advantages such as stronger separation performance, fewer reaction by-products, less corrosion, more environmental protection, and continuous production. As an acidic or basic functional polymer, ion exchange resin has been widely used in esterification, hydrolysis, condensation, dehydration, carbonylation, hydrogenation and other reactions. Different types of resins are available as commercial catalysts, and their differences in polymer matrix, functional groups and final reaction behavior determine their catalytic activity and selectivity. Factors to be considered in selecting catalyst resins include resin type, temperature, dry weight capacity, catalyst porosity, and catalyst expansion/contraction. Amerigo Scientific offers catalyst resins that often used in chemical and petrochemica

Physicians and scientists face the challenge of keeping organs, tissues, and cells viable during various transportation and storage processes for research needs. General products on the market are designed to keep organs, tissue samples, and cells alive for up to 24 hours. Amerigo Scientific offers a solution to preserve tissues, organs, and cells for a longer period for the benefit of physicians and scientists around the world. T-STORE® is a series of sterile, chemically defined, and optimized media that provide a stable storage and shipping environment for mammalian tissue samples and cells. The composition of the medium used to nurture the samples during the preservation protocol is very important, as many factors can negatively affect the integrity of proteins, DNA and RNA in tissues or cells. T-Store® utilizes a robust buffering system, allowing its use over a wide temperature range (+2 °C to +37 °C). In addition, T-Store® is isosmotic, isotonic and isoionic with human serum an

Nucleoside phosphoramidites are derivatives of natural or synthetic nucleosides that are used to synthesize oligonucleotides, relatively short fragments of nucleic acid and their analogs. Oligonucleotides are widely used in biological research as effective tools to regulate gene expression and have also been developed as therapeutics. Therapeutic oligonucleotides are usually modified to enhance their stability and specificity and to minimize the side-effects. They include antisense oligonucleotide, small interference RNA (siRNA), ribozyme (RNA enzymes) and deoxyribozymes (DNA enzymes), CpG oligodeoxynucleotides (CpG ODN), transcription factor decoys, and aptamers. In various oligonucleotide synthesis methods, the phosphoramidite method is the most preferred one as it best meets the criteria for viable synthesis of oligonucleotides. The synthesis approach is suitable for the synthesis of long oligonucleotides with modified backbones, which are difficult to prepared by other methods.